MMJ vs Brain Aging


Researchers at the University of Bonn and Hebrew University have discovered that low, regular doses of tetrahydrocannabinol (THC), one of the main active ingredients or cannabinoids found in marijuana, may help to keep our brains from 'slowing down' as we get older. Published today in the journal Nature Medicinethe German study revealed that while younger mice suffered a performance drop under the influence of THC, the psychoactive chemical gave older mice a considerable performance boost, even putting them on par with younger mice who'd abstained.

To test the chemical's effect on brains of different ages, researchers put mice that were two months, one year, and 18 months old on a daily regimen of THC over the course of a month. The mice were then tested on their abilities to recognize familiar objects and to navigate a water maze in known and new configurations. 

As has been similarly observed with humans, younger animals excelled at the tests when 'sober' but tended to struggle significantly under the influence of THC. "Mature" and "old" mice, on the other hand, struggled with tasks as consistent with their brain ages at first but saw a huge increase in performance with THC infusions that raised their skill level up to young mouse (drug-free) standards and continued for weeks afterward. Meanwhile, The Guardian reported, "None of the mice displayed the strange effects one might expect from doses of THC." 

Overall, the results seem to support researchers' belief that the benefits for older mice are a result of stimulating the brain's endocannabinoid system, a biochemical pathway in both mice and human that grows less active over time. The scientists noted, "Together, these results reveal a profound, long-lasting improvement of cognitive performance resulting from a low dose of THC treatment in mature and old animals."


More at: Forbes

Stoner Gift Ideas Under $50 The M.E.T.R.O. Pipe


The M.E.T.R.O.
by: High Tech Pipes

M.E.T.R.O. Pipe is compact, lightweight, built tough and designed to express old world craftsmanship with its brass finish. M.E.T.R.O. Pipe fits in your pocket, it’s spill proof, indestructible and makes traveling easy with built-in herb storage compartment. 

The swivel mouthpiece doubles as bowl cover to stuff out burning herbs - life the mouthpiece slightly to open the storage. 

Built from medical grade billet aluminum and anodized, M.E.T.R.O. will last for many years without deteriorating. 

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Terpineol the Cancer Killing Terpene


With terpene science becoming more and more prevalent in our regular lives in the cannabis community, there is more scientific research, developments and innovation being done with terpenes, which is great for medical professionals and even greater for medical patients looking for natural alternatives to synthetic and toxic pharmaceuticals.

Of all the terpenes—and there are over 30 different terpenes found in the cannabis plant—there is one that stands out as one of the most beneficial and most powerful; powerful enough to even kill cancer cells and tumors. Alpha-terpineol has been proven to be an anticancer agent in multiple studies. In August 2000, June 2010 and July 2016, alpha terpineol was proven to not only be a powerful cancer-killing agent, it was also proven to be a powerful antioxidant, antibiotic, antidepressant and it was proven to reduce inflammation and pain.

Terpineol creates a floral aroma, often resembling lilacs, clove, citrus, or even apple blossoms. It can also remind one’s olfactory senses of eucalyptus sap. From a flavor perspective, terpineol tastes like mint and anise. Alpha-terpineol has also been proven to have sedative properties, great for relaxing and helping people to sleep. Along with CBN, it is one of the terpenes and cannabinoids that help some strains of cannabis provide a couch-lock effect, sedating and relaxing consumers to the point that their bodies feel heavy and immovable.

The medical journal Anticancer Research published a Swedish research study in June 2010, led by Dr. Saadia Bashir Hassan, and the team found alpha-terpineol to be an anticancer and antitumor agent. The Swedish research from the University Hospital in Uppsala, Sweden revealed that alpha terpineol might be especially helpful for patients with small cell lung carcinoma. “The results suggest that alpha terpineol inhibits the growth of tumor cells through a mechanism that involves inhibition of the NF-?B pathway,” the study stated.

The study from August 2000 was published in the journal Phytotherapy Research and found 4-terpineol to be a powerful antioxidant with “respectable radical scavenging property” as well.

The study from 2016, published in Chemico-Biological Interactions concluded alpha-terpineol (?TPN), when combined with ?-cyclodextrin (?CD) efficiently reduced hyperalgesia and chronic muscle pain, proving that terpineol can be used for serious inflammation treatment and pain treatment, and specifically could treat patients suffering from fibromyalgia.

An additional study from 2014 found that ?-terpineol kills cancer cells and induces apoptosis in patients with liver cancer that also suppresses tumor cell growth. Science Direct published a study from June 2015 that found alpha terpineol kills cancer cells and inhibit tumor growth as well.

Terpineol is just one of the many beneficial plant-based medicinal compounds that is being studied currently to try and utilize more natural medicines in the treatments of serious illnesses, but so far it is one of the most powerful. It is exciting to see the scientific community support cannabinoid research and cannabinoid therapies over pharmaceuticals; now we just need the FDA and DEA to get behind this science so the majority of the public can not only know about this information but have safe access to alternative natural therapies that utilize cannabinoids, and the cannabis plant.

Medical Cannabis Could Be the Solution to the Opiate Epidemic


For ages, medical marijuana activists have suggested that medical marijuana is not only safer than opiates but more effective as a long-term solution to chronic pain – and many patients agree, even suggesting that medical cannabis has helped them to reduce or eliminate the use of opiates in their lives.

Previous studies have suggested that these statements are very true, finding that in states where medical marijuana is legal, prescription opiate use has dropped significantly (as well as other prescriptions that may be replaced by medical marijuana such as those of epilepsy and Parkinson’s for example). As a result of that, these studies found that there are less opioid-related deaths and overdoses in states where medical marijuana is available.

“Medical marijuana legalization was associated with 23% and 13% reductions in hospitalizations related to opioid dependence or abuse and [opioid pain reliever] OPR overdose, respectively; lagged effects were observed after policy implementation.”

A more recent study goes with a slightly different route, looking at the number of hospitalizations that were considered related between the years of 1997 and 2014, during which time many of the states with legal medical marijuana passed their laws and implemented their programs. The University of California researchers found an interesting trend – not only a reduction in opiate-related hospitalizations but also no increase in cannabis-related ones. Also, the longer medical marijuana was available, the more the number of hospitalizations dropped.

“This study demonstrated significant reductions on OPR- (opioid pain reliever) related hospitalizations associated with the implementation of medical marijuana policies. … We found reductions in OPR-related hospitalizations immediately after the year of policy implementation as well as delayed reductions in the third post-policy year.“

This evidence clearly suggests that rather than causing the opiate epidemic, cannabis is actually helping to save people from it. Some states are even trying to get opiate addiction added to the list of qualifying conditions for medical cannabis – although it’s a tough sell to lawmakers who are still so uncertain of how to go about this issue. However, every state that allows medical cannabis for chronic pain is one more that will likely see thousands of lives saved when a safer alternative is finally available to those who need it.

Stoner Gift Ideas Under $100 The Nail Crown Flower Edition


The Nail Crown 
Flower Edition
from Cruz Culture

The Nail Crown Flower Edition is the perfect multi-tool for anyone who enjoys dry herb products. This multi-tool kit comes with the world’s first and only silicone encased patented grinder. Don’t worry about your grinder banging into things; with its soft silicone cover, it protects itself and everything around it.

Multi Tool Features Included: Silicone Encased Grinder, Lighter Holder, Papers Holder, Large Container, Small Container, One Hitter, Large Crutch, Small Crutch, Clip Tool, Poker Tool, Packer Tool and Tool Stand

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