MMJ Medicinal Marijuana vs Lupus

Cannabis is effective against lupus for several reasons. Many of the anti-inflammatory benefits it delivers are closely related to the relief gained by rheumatoid arthritis sufferers who medicate with the herb. Chiefly, marijuana is a very effective analgesic (pain killer) and anti-inflammatory agent. Because the inflammation associated with lupus can produce considerable pain in the hands and knees, cannabis can both treat the source of the symptom — the inflammation and swelling — while also decreasing one of the main symptoms — pain.

Some lupus patients report gaining the most efficacy from their symptoms from strains and extracts of cannabis that are high in the non-psychoactive cannabinoid CBD (cannabidiol). Others claim relief from juicing the leaves of cannabis plants, with CBD-rich strains being indicated as more therapeutic. Most strains and concentrates of cannabis are extremely effective at dealing with the nausea experienced by some lupus patients. Those suffering from insomnia should consider smoking or vaporizing a potent indica before sleep.

The fact that lupus sufferers gain the greatest relief from cannabis strains high in CBD is no surprise. The disease affects the immune system, the areas of the body in which the greatest number of CB2 receptors are found. CB2 receptors are the microscopic chemical parking spaces located throughout the body that features what researchers label a “high binding affinity” for the CBD cannabinoid molecule. THC, the cannabinoid most responsible for the psychoactive effect of cannabis that’s so great for depression and PTSD, binds with a different cannabinoid receptor, CB1, which is found mostly in the brain and nervous system.

Because so many lupus patients suffer from skin conditions, the use of cannabis topicals is one of the most effective treatments for varieties and symptoms of this disease that affect the epidermis. This is especially true based on the stigma of highly visible skin conditions in western cultures that value physical beauty. Topicals and the improvement of skin quality are also an approach that considers psychological, emotional, and self-esteem issues, especially in young and middle-aged women typically afflicted with lupus.

Conventional pharmaceutical treatments for lupus include steroids and immunosuppressants, such as methotrexate. In some patients, methotrexate can cause pulmonary fibrosis, among many other negative and severe side effects. Many drugs used to treat lupus also result in extreme nausea and abdominal cramping.

Cannabis, on the contrary, conveys no severe or negative side effects, unless one considers an improved mood, an appetite, and better sleep undesired results of one’s medicine. Given the extreme efficacy of cannabis for inflammation and pain, especially top-shelf strains high in CBD — and the almost complete lack of negative side effects from the herb — one must question the moral and ethical validity of the anti-cannabis stance of the medical establishment.

In some cases, chemotherapy (and, specifically, a pharmaceutical drug called cyclophosphamide [Cytoxan] that is also used to treat cancer) is used to treat patients suffering from lupus. This avenue of therapy brings a slew of negative and controversial side effects to lupus patients, including severe nausea and vomiting, hair loss, lack of energy, and depression, among many others.

Much more at: MassRoots

THC Tetrahydrocannabinol vs Alzhemer's Disease

Alzheimer’s disease may now be added to a list of diseases with promising treatment from cannabis compounds, a new study from the Salk Institute says.

While there has been research and trials to use compounds to treat chronic pain, cancers, epilepsy, and other diseases and illnesses, this laboratory study is the first of its kind to test tetrahydrocannabinol (THC), a main component in marijuana, against the plaque buildup of the brain associated with Alzheimer’s disease.

The researchers took human neurons that they grew in a lab and altered them so that they created the plaque buildup (comprised of proteins such as beta-amyloid). The researchers then subjected the neurons to amounts of THC and other marijuana compounds.

What they found was that not only did the THC cause a breakdown of the protein buildup, but a reduction in inflammation in the cells. ​Inflammation is bad because it makes it harder for your neurons to communicate with one another correctly.

"Although other studies have offered evidence that cannabinoids might be neuroprotective against the symptoms of Alzheimer's, we believe our study is the first to demonstrate that cannabinoids affect both inflammation and amyloid beta accumulation in nerve cells," says Salk Professor David Schubert, the senior author of the paper said in a statement.

This study is also novel because the research also provides a stronger link between protein buildup and the inflammation of the neurons. Some past hypotheses had thought that other immune-like cells had been inflamed, and not the neurons themselves.

The researchers believe that the THC was able to reduce the protein buildup and inflammation by working in the brain’s endocannabinoid receptors, which are naturally occurring in the body. Scientists had already known that exercise engages these receptors, and physical activity can slow the progression of Alzheimer’s disease.

Schubert and his fellow researchers had found in a previous study that the endocannabinoid receptors were involved with the removal of protein buildup and inflammation when testing a new drug. The researchers then decided to investigate the relationship with THC and Alzheimer’s plaque.

Much more study must be conducted before a causal link can be suggested between THC and beta amyloid, the researchers say, including human clinical trials. These exploratory laboratory models are just the beginning.

More from: Popular Science

RECIPE Espresso CannaCupcakes by Jeffthe420chef

Number of servings: 12
Preparation Time: 20 minutes 
Bake time: 18-20 minutes

10-*15mg per serving 

  • 1 cup all-purpose flour
  •  ½ teaspoon salt
  •  ½ teaspoon baking powder
  •  1 teaspoons baking soda
  •  ½ cup unsweetened cocoa powder
  •  ½ cup Cane Sugar
  •  ½ cup Brown Sugar
  •  1 stick grass fed butter, melted
  •  ½  cup hot coffee
  •  ½ cup milk
  •  3 egg yolks
  •  1 teaspoon almond extract
  •  1 tin Kiva Terra Espresso Beans
  •  1 16 oz. bar dark chocolate or 50g Kiva Espresso Dark Chocolate bar *(+5mg per serving)
  •  ½ cup bittersweet chocolate chips
  •  ½ pint heavy whipping cream

1. Preheat oven to 340°F.
2. Grind 12 Terra Espresso Coffee beans
3. In a large mixing bowl, sift together dry ingredients.
4. Add melted CannaButter, coffee and milk and mix at medium speed for 2 minutes. Add eggs, almond extract and ground Terra Espresso beans. Beat 2 more minutes.
5. Pour into paper lined muffin tins pans (3/4 full).
6. Bake for 20-22 Mins

Ganache Icing & Coffee Bean Crumble
1. Coarsely Grind chocolate bar and chocolate chips and set aside in a large glass bowl
2. In a small saucepan, heat whipping cream and stir constantly until edges start to bubble
3. Pour hot cream over chocolate through a strainer and stir until ganache is dark, silky and smooth.
4. Refrigerate for 1 hour to thicken a bit
5. Invert cupcake and dip top into ganache. Set aside.
6. For coffee bean crumble, place 12 Terra Espresso Beans into food processor and pulse until desired coarseness.
7. Sprinkle ½ teaspoon over each cupcake

 VoilĂ !


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