MMJ vs Fear and Anxiety Disorders

According to a study conducted by researchers at four universities and published by the British Journal of Pharmacology, the CBD cannabinoid could benefit those suffering from “anxiety-related and substance abuse disorders.”

Generally speaking, Americans are a relatively apprehensive group. Approximately 18% – roughly one in five – suffer from some form of anxiety related illness; another 23.5 million Americans over the age of 12 suffer from some form of substance abuse. Potentially challenging the $2 billion anti-anxiety pharmaceutical market, and helping millions of Americans overcome their addiction, the 2017 study reports, “the effects of Cannabidiol on fear memory processing indicates that it reduces learned fear in paradigms that are transnationally relevant to phobias and post-traumatic stress disorder.”

Conducted by researchers from the School of Psychology at the University of Birmingham, the University of Nottingham, the University of São Paulo and the Federal University of Santa Catarina, the study found:

“Cannabidiol, the main non-psychotomimetic phytocannabinoid found in Cannabis sativa, reduces anxiety via 5-HT1A and (indirect) cannabinoid receptor activation in paradigms assessing innate responses to threat. Cannabidiol does so by reducing fear expression acutely and by disrupting fear memory reconsolidation and enhancing fear extinction, both of which can result in a lasting reduction of learned fear.”

By utilizing animals for their scientifically based research, the study discovered the CBD cannabinoid “regulates emotion and emotional memory processing,” which could eventually lead to a CBD-based treatment for America’s overly medicated and anxiety-riddled population.

Findings: “Importantly, CBD produces an enduring reduction in learned fear expression when given in conjunction with fear memory reconsolidation or extinction by disrupting the former and facilitating the latter. This makes CBD a potential candidate for testing as a pharmacological adjunct to psychological therapies or behavioral interventions used in treating PTSD and phobias.”

In summary, the scientists concluded, “This line of research may lead to the development of a formulation of CBD for use as a treatment for anxiety related and substance abuse disorders in the future.”

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