Medical Marijuana as Treatment for Parkinson's Disease

Much about Parkinson’s Disease remains unclear. Nobody knows the true cause of the disease and scientists are still searching for a cure. What we do know is that Parkinson’s is a degenerative condition that depletes dopamine centers within the brain. Recent research has shown positive results when utilizing cannabis for Parkinson’s Disease treatment.

What Are Parkinson’s Effect On The Human Body?

The loss of dopamine causes these common symptoms: body tremors, muscle spasms, loss of balance, insomnia, memory loss and dementia. What is most frightening about Parkinson’s Disease is the fact that it is progressive. What may start out as the occasional finger twitch can lead to the inability to freely move certain muscles. These symptoms of Parkinson’s makes it extremely difficult to accomplish daily tasks.

The root causes of Parkinson’s Disease are unknown and current medications only dull its symptoms.Over time, many patients build up a tolerance to these treatments, which cause their symptoms to eventually return. Some Parkinson’s patients are now finding relief through medical cannabis treatments.

Science Behind Using Cannabis For Parkinson’s Disease

Recent scientific research into how Parkinson’s affects our neurological structure has uncovered how the disease attacks the dopamine centers within the basal ganglia. The basal ganglia helps control muscle mobility and is one of the key regions in the brain that Parkinson’s attacks. The basal ganglia has a surprisingly high amount of endocannabinoid receptors that consist mostly of CB1 receptors; the receptors where endogenous THC is activated when it reaches the brain.

Cannabis’ ability to be a neuro protector has been discussed and researched for decades. A study conducted nearly twenty years ago researched whether or not cannabis had neuroprotective qualities. Researchers injected rats with a neurotoxic chemical that typically severely decays the brain. When given cannabis extracts, the rat’s brains were protected from the chemical. The groundbreaking study proved that cannabis has inherent neuroprotective qualities.

Cannabis Is A Reliable Neuroprotectant

A reliable neuroprotectant that could treat Parkinson’s would be very welcome. While the research proving cannabis is a reliable neuroprotectant is promising, it is scarce. There is not enough cannabis research to prove definitively that cannabis can effectively treat Parkinson’s disease, but the anecdotal evidence is overwhelming.

According to multiple firsthand accounts, patients can find relief by using medical cannabis. In states where medical marijuana is legal, those with Parkinson’s have began exploring alternate treatments with medical cannabis. As more states continue to legalize marijuana use, more patients will have the ability to discover the medicinal qualities of cannabis for Parkinson’s disease.

Stoner Gift Ideas Under $40 The Glass Sherlock Pipe by Grav Labs

The Glass Sherlock Pipe
by Grav Labs

These glass Sherlock pipes, at only 6-inches in length, is the perfect traveling companion for smokers worldwide. Discretion when smoking is sometimes extremely valuable and glass Sherlocks like these are the definition of "stealthy." Even though this hand pipe is the larger size, slipping it quickly inside your pocket or bag is no problem, and your privacy is protected. 

Unlike some other brands, Grav Labs glass merchandise doesn't need special precautions to keep it safe. Only the best lab-grade borosilicate is used in any of their products, and the toughness of that substance is legendary. These awesome glass Sherlock Pipes come in a variety of colors, and it may be difficult to choose just one. 

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MMJ Football and the CTE Crisis

Persistent vomiting, three-day bouts of confusion, unprovoked rage, self-harm, suicidal impulses -- those are just some of the horrifying symptoms of chronic traumatic encephalopathy (CTE), a degenerative brain disease that afflicts up to 99 percent of retired NFL players thanks to the severe concussions that have become everyday injuries in pro football.

CTE is jeopardizing the lives of players as well as the reputation of the NFL, but medical marijuana could restore both to good health. 

A recent study published by the Journal of the American Medical Association revealed the prevalence of CTE among retired NFL players. After analyzing 111 brains of deceased players whose bodies were donated for research, scientists found that 110 of the 111 specimens (99 percent) had developed CTE.

Researchers noted their results might be somewhat skewed since the families of those donors suspected that their loved ones had developed CTE. But there's no denying that CTE is a real and prevalent threat to the lives of NFL players. But the disease often begins to take root in their teens.

According to the study, approximately 3 in 14 high school players (20 percent) develop CTE, which can begin showing symptoms in their mid 20s. The rates rise to 48 out of 53 college players (90 percent) and climb steadily among long-tenured NFL players. That means every game increases the risk of developing the lethal condition, which can't be detected until after it claims the player's life. 

CTE can only be diagnosed after death. So there is no way to identify and cure the illness before it takes hold, but there might be a way to mitigate and perhaps reverse its symptoms. 

Medical Marijuana Could Help NFL Players
There's no cure for CTE, but cannabis could protect the brain from the damage caused by repeated concussion. The neuroprotective properties of cannabis could make players more CTE-resistant, according to Lester Grinspoon -- a Harvard professor of psychiatry. And tetrahydrocannabinol (THC) -- the psychoactive ingredient in marijuana -- also stimulates parts of the brain involved in healing after a traumatic brain injury.

So marijuana might not only reduce but perhaps reverse the effects of CTE. 

That's why retired players like Eugene Monroe and Kyle Turley are calling on the NFL to repeal the league’s ban on cannabis and support medical marijuana research that could lead to a CTE breakthrough. 

"I suffer from traumatic brain injury from playing this sport. I've seen this firsthand in multiple scans of my brain," Turley told Freedom Leaf last year.

Turley added that allowing athletes to use medical marijuana could save the lives of players like him as well as the sport itself. "If we want to save football, then we've got to start looking at solutions, not just count concussions. Cannabis is that potential savior."

Read More at: Civilized

MMJ Drug Could Extend the Lives of Brain Cancer Patients

UK drug maker GW Pharmaceuticals announced it has achieved positive results in the second phase of a clinical study on Glioma, a cannabinoid-based therapy aimed at treating an aggressive form of brain cancer.

The study looked at 21 patients with recurrent glioblastoma multiform, or GBM, and found that participants who were given the drug—a combination of THC and CBD—lived significantly longer than those who took a placebo.

“These promising results are of particular interest as the pharmacology of the THC:CBD product appears to be distinct from existing oncology medications and may offer a unique and possibly synergistic option for future glioma treatment,” the study’s principal investigator Susan Short, an oncology professor at the Leeds Institute of Cancer and Pathology at St. James University Hospital, said in a statement.

Study participants who received Glioma showed an 83 percent one-year survival rate, GW reported, compared to a 52 percent rate among those who took a placebo. The median survival rate was 550 days among those who took the drug and 369 days among those who did not.
While the company says the treatment was “generally well tolerated”  by patients, there were some observed side effects.  Most common were vomiting, dizziness, nausea, headache, and constipation.

GBM, one of the most common types of brain tumor, is an aggressive cancer that arises in the brain or spinal cord. It carries a poor prognosis, with only 28.4 percent of patients surviving longer than a year after diagnosis. Only 3.4 percent of patients survive to year five.

CEO Justin Gover said in a statement that the latest results continue to validate the importance of researching cannabis as a treatment for cancer and other diseases.

“These data are a catalyst for the acceleration of GW’s oncology research interests,” he said, “and over the coming months, we expect to consult with external experts and regulatory agencies on a pivotal clinical development program for THC:CBD in GBM and to expand our research interests in other forms of cancer.”

Read More At: Leafly

VIDEO EDIBLE RECIPE Pot Jello Shots by Mary Jean

Baked Episode 8
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Stoner Gift Ideas Under $20 The Glass Bubble Bowl by GravLabs

The Glass Bubble Bowl
by Grav Labs

Beautiful, functional, smoking art all describe this Glass Bubble Bowl. 

It's made of the same durable borosilicate as any of Grav Labs glass items. You may lose it somewhere but you don't have to worry about breaking it. The bumps near the top are more than just decorative, they also make this Bowl very easy to hang onto. 

Spare bowls are always a good idea, and since this price is not a budget breaker, you don't have to choose from the assorted colors available, just get one of each. 

This bowl has the kind of quality that can be felt. As soon as you hold in your hand, you will know what true craftsmanship feels like. 

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REVIEW The Fumo Pipe

The Fumo Pipe is a new twist on the old steamroller. Made from a solid billet of aluminum, stainless steel bowl-piece a stainless steel push-button carb and a polycarbonate smoke chamber, the Fumo Pipe is near indestructible.

Strong and sturdy is always good but how does it smoke? Well, to be brief, pretty darn good. The design and engineering take advantage of heat-syncing of the aluminum providing some cooling but the trick is storing the Fumo Pipe in the freezer. Either way, chilled or right out of the box, the Fumo Pipe delivers a cooled hit.

I have certainly given my Fumo Pipe a workout and everyone I have shared it with agree that the pipe is worth having it in any collection. Even with all of the testing and sharing, my pipe hasn’t clogged yet. The pipe cleaned up quickly and easily with a little alcohol, a couple of cotton swabs and a paper towel.

Overall, I give the Fumo Pipe an “A”. Unique and clever design, good smooth smoke and easy to maintain. I couldn’t ask for more.

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5 Facts about the 1937 Marihuana Tax Act

The Marihuana Tax Act of 1937 was drafted by infamous anti-cannabis prohibitionist Harry Anslinger, and signed into law on August 2, 1937. Up until this law was passed, cannabis products were legal to sell in pharmacies and drug stores, so long as they were properly labeled and regulated, but it was during the 1930s that the mainstream attitudes towards cannabis began to sway greatly towards negative opinion.

1. The Origins of ‘Marihuana’
This was one of the first acknowledgments by the US government of the new and notorious drug known as “marihuana.” The name itself, marihuana, was derived from Mexican Spanish, although the linguistic origins have been widely debated. From the Aztec language Nahuatl to the Chinese word ma ren hua, meaning “hemp seed flower,” marijuana truly has many roots, but the word was popularized by Harry Anslinger as part of his campaign to instill fear of the drug. Before this, it was commonly referred to as "hemp" or “cannabis sativa,” and was considered “a fashionable narcotic,” often found in over-the-counter pharmaceutical products like cough syrups.

2. The Opposition of the AMA
The Marihuana Tax Act of 1937 was originally passed to levy taxes on hemp products and on the commercial sales of cannabis products. Farmers could acquire tax stamps for the cultivation of fiber hemp, physicians would be charged a tax for prescribing cannabis, and pharmacists would be required to pay a tax for selling cannabis. The American Medical Association was strongly opposed to the act, arguing against the measure in court and proposing instead that cannabis be added to the Harrison Narcotics Tax Act.

3. Reefer Madness Is Born
The law was enacted a year after the production of the notorious anti-cannabis film, Reefer Madness, originally titled Tell Your Children, but also known as The Burning Question, Doped Youth, and Love Madness. Reefer Madness was financed by a church group before being widely released as an exploitation film to warn the public about the dangers of cannabis use. It was just one in a long line of education-exploitation films of the era, including Marihuana (1936), Assassin of Youth (1937), and Devil’s Harvest (1942).

4. The Power of the Paper Industry
Over the years, many have speculated that the reason for the campaign against cannabis boiled down to demonizing the hemp industry because it was a low-cost substitute for paper pulp. The paper industry, and more specifically, the newspaper industry, led the charge against cannabis with Anslinger. William Randolph Hearst, Andrew Mellon, and the DuPont family all had major investments in the timber and newspaper industries, and a rise of hemp would have seemingly undercut their profits. Curiously, years later, manufacturing paper with hemp as the raw material proved that hemp lacks the qualities needed to become a major competitor of the traditional paper industry, as it does not contain a high enough concentration of cellulose to be an effective substitute.

5. The First Victim of the Drug War
The first person to be arrested under the Marihuana Tax Act of 1937 was precisely the person Anslinger and his cohorts sought to target with their cannabis crusade: a young, Mexican-American named Moses Baca, who had a quarter-ounce of cannabis tucked into his drawer in his third-floor rooming house in Denver’s Five Points neighborhood. Judge John Foster Symes sentenced Baca and made his disgust for cannabis well-known: “I consider marijuana the worst of all narcotics, far worse than the use of morphine or cocaine. Under its influence, men become beasts. Marijuana destroys life itself. I have no sympathy with those who sell this weed.”

via: Leafly

Nearly Half of people who use CBD products Stop taking Traditional Medicines

The largest survey on cannabidiol or CBD usage to date found that women were more likely than men to use CBD and once they started using it, were likely to drop their traditional medicine. A new survey from Brightfield Group and HelloMD covered 2,400 of HelloMD’s community of 150,000 members and did a deep dive into the usage of CBD products and their effectiveness. HelloMD is an online community that brings together doctors and cannabis patients.

Cannabidiol is a non-psychoactive cannabis compound that doesn’t give users the feeling that they are high or stoned. Instead, it is known to have medicinal qualities. Contrary to the image of men being the predominant consumers of cannabis, this survey found that 55% of the CBD users were women, while men preferred the THC-dominant products. Brightfield Group, which helped conduct the survey, studies consumption patterns and demand trends and is committed to providing accurate data in the cannabis industry which seems to be rife with unsupported claims.

The most common reasons people used CBD were to treat insomnia, depression, anxiety and joint pain, according to Dr. Perry Solomon, the Chief Medical Officer of HelloMD. Forty-two percent of the CBD users said they had stopped using traditional medications like Tylenol pain relievers or prescription drugs like Vicodin and had switched to using cannabis instead. Eighty percent said that they found the products to be “very or extremely effective.” Only 3% or less found the product to be either ineffectual or only slightly effective.

One of the areas that the CBD producers will have to work on is educating the consumer about CBD products. There are more than 850 brands of marijuana-derived CBD products on the market and 150 hemp-derived products. (Marijuana and hemp are the two variations of the cannabis plant.) Eight percent of the consumers surveyed admitted they didn’t know which CBD product they had used.

Adding to the confusion is the murky legal status of CBD. Technically, the U.S. Drug Enforcement Agency (DEA) labels all CBD products as illegal. However, hemp-derived CBD is available in just about every state and even online through Amazon. Marijuana-derived CBD tends to only be found in states with legal medicinal marijuana.

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